作者：陈艳;李铁军;俞光岩;史作慧;摘要：目的:探讨口腔婴儿黑色素神经外胚瘤的诊断要点及治疗原则。方法:对北京大学口腔医学院1980年至2007年8月间收治的13例口腔婴儿黑色素神经外胚瘤病例进行回顾性研究,复习临床资料及病理切片。结果:9例口腔婴儿黑色素神经外胚瘤发生于上颌骨,3例位于下颌骨,1例位于颊部。发病年龄从2个月至7个月。临床症状均为肿物,5例术前检查发现肿物为紫红色或蓝黑色。肿物生长迅速,3例术前诊断为恶性肿瘤,仅有1例术前临床诊断为婴儿黑色素神经外胚瘤。9例有随访结果,2例确定复发,复发时间均为术后1个月,1例死亡。1例切除不完全的病例术后19年无复发。结论:口腔婴儿黑色素神经外胚瘤具有典型的发病部位与发病年龄,临床检查时应注意肿物的颜色。肿瘤常生长迅速,具有局部侵袭性。对患者术后半年内要密切随访;病理诊断要与儿童小圆细胞恶性肿瘤相鉴别;相对保守的手术为首选治疗方式。

作者：徐丽莉;李铁军;摘要：目的:检测伴痣样基底细胞癌综合征(nevoid basal cell carcinoma syndrome,NBCCS)牙源性角化囊性瘤(keratocystic odontogenic tumor,KCOT)中是否存在PTCH2基因的异常。方法:收集15例NBCCS相关的KCOT患者的新鲜病变组织和外周血标本,提取DNA,采用PCR直接测序法进行PTCH2的突变分析。结果:发现2例尚未报道的错义突变(c.323T>C,c.1319C>T),分别引起1个氨基酸的改变,另发现9处PTCH2的多态性位点,其中3处为尚未报道的新位点。结论:虽然在NBCCS患者中PTCH2突变不如PTCH1突变频发,但少数NBCCS相关的KCOT患者可发生PTCH2的胚系突变,其病理学意义有待进一步研究。

摘要：2007年11月16日中国医师协会第四届“中国医师奖”颁奖仪式在人民大会堂隆重举行,北京大学口腔医学院著名口腔颌面外科专家王兴教授喜获殊荣。王兴教授此前于2006年曾获中国医师协会口腔医师分会颁发的“...

作者：林久祥;许天民;摘要：Orthodontics in China has experienced two important stages. At its early stage from 1950 s to 1970 s orthodontics was a division of prosthodontic department in China. There were 3 top professors in this field, who got partly training at one time or another in USA and returned to China working in Beijing Medical College, the Fourth Military Medical University and Shanghai Second Medical College. Among them, Professor Mao of Beijing Medical College was regarded as the father of Chinese Orthodontics. Removable appliance was the main tool at that stage and Prof.Mao brought forward Mao’s Classification of Malocclusion which is still used in China. The rapid developing stage began in the 1980 s when China opened its door to the world. More and more orthodontists got further training abroad and brought back advanced techniques since then. Up to now, we have already had more than one thousand of orthodontic specialists and established its own organization——the Chinese Orthodontic Society (COS), which holds domestic orthodontic meetings and organize its members to attend international meetings. Right now, almost all advanced techniques in diagnosis and treatment...[查看详细内容..]

作者：王勇;摘要：口腔修复计算机辅助设计与制作(computer aided design/computer aided manufacturing,CAD/CAM)系统自上个世纪80年代问世以来,一直为我国口腔界所关...

作者：马莲;摘要：唇腭裂是发生在口腔颌面部的最常见的面裂(facial cleft)之一,发病率在全球平均约1/600。唇裂(cleftlip)和腭裂(cleft palate)可以单独发生,也可以合并发生为唇腭裂(c...